英语翻译METHODS Selection of Studies To identify RCT concerning

英语翻译
METHODS
Selection of Studies
To identify RCT concerning the efficacy of bisphospho-
nates in the prevention of vertebral,hip,and nonverte-
bral-nonhip fractures in postmenopausal osteoporotic
women,a systematic literature search was performed.A
systematic literature review performed by Stevenson and
coworkers in 2005 (2) provided relevant studies pub-
lished before October 2002.To identify additional rele-
vant evidence published between October 2002 and June
2007,Medline,Embase,and Cochrane databases were
searched using a similar search strategy as used by Stevenson
and coworkers (2).Search terms included a combination of
free-text and thesaurus terms relevant to osteoporosis,post-
menopausal women,fractures,the bisphosphonates of inter-
est,and RCT.
\x05Two reviewers independently evaluated each identified
study against the following predetermined selection criteria:
Type of Design
The type of design of the study was RCTs with a double-
blind period and a follow-up of 3 years (or 2 years if used
for registration purposes).Only full-published reports
were considered; letters and abstracts were excluded.
Intervention
The intervention of at least 1 study group included 1 of
the following bisphosphonates:alendronate,etidronate,
ibandronate,risedronate,or zoledronic acid.
Study Population
The study population consisted of postmenopausal
women with osteoporosis.
Outcome Measure
The outcome measures were vertebral fractures (morpho-
metric),hip fractures,and nonvertebral-nonhip fractures.
Nonvertebral-nonhip fractures include all fractures re-
ported other than vertebral and hip fractures.

方法
研究选择
为了鉴定关于预防在绝经后骨质疏松性椎体,髋关节,和非脊椎非髋部骨折妇女的二膦酸盐的有效性的随机对照试验,需要进行系统的文献检索.在2005年由Stevenson和合作者们进行的系统文献检索审查提供了相应的研究,在2002年10月之前出版了.为了鉴定在2002年10月和2007年6月间出版的补充的相关佐证,人们用了和当时Stevenson和合作者们使用的类似的搜索策略在Medline,Embase,和 Cochrane 数据库中进行搜索.搜索字词条件包括自由文本和与骨质疏松症,后更年期（绝经）妇女,骨折,双膦酸盐的利益,随机对照试验相关的词库条款.
两个评论家单独评估了每一个对以下预定的选择标准的确认研究：
设计类型
研究的设计类型是有双盲期和3年后续（如果目的为登记的话是2年）的随机对照试验.只有完全出版的报道才会被考虑；信件和摘要排除.
干预
对于至少1个研究小组的干预包括下列二磷酸盐之一：阿仑膦酸钠,依替膦酸钠,伊拜膦酸盐,利塞膦酸钠或唑来膦酸.
研究人群
研究人群由绝经后患有骨质疏松症的妇女组成.
结果测量
结果的测量是椎体骨折（形态）,髋部骨折,和非椎骨非髋部骨折.非椎骨非髋部骨折包括所有被报道过的骨折以外其他椎体和髋部骨折.