酶催化合成高纯度精细化工产品

酶催化合成高纯度精细化工产品
请问哪位知道关于它的原理、过程或者应用的?在做一个这方面的知识了解,希望大家能多多指教.万分感激.

研究了无溶剂体系中脂肪酶LRI催化合成甘油中碳酸单酯(MG).得到适宜的反应条件为:反应温度57℃,n(酸)∶n(甘油)=1∶1 1,加酶量100U/g(酸),甘油初始含水量w(H2O)=12%,封闭物系反应4h转敞开物系反应6h.产物中甘油中碳酸单酯质量分数w(MG)=42 20%.将n(酸)∶n(甘油)降低至1∶9,反应时间缩短至4h,粗产物经脱甘油和脱酸处理,可获得高纯度甘油中碳酸单酯.纯化后产品中基本不含游离酸及甘油,其中甘油中碳酸单酯质量分数w(MG)=73 65%.过量加入的甘油全部可以回收利用,其平衡转化率降低不超过2%.
【作者单位】：江南大学化学与材料工程学院;江南大学化学与材料工程学院;江南大学化学与材料工程学院 江苏无锡 214036;江苏无锡 214036;江苏无锡 214036
【关键词】：脂肪酶;甘油中碳酸单酯;酶催化合成
【基金】：江苏省科委基金资助(BJ99036)
【分类号】：TQ423
【DOI】：cnki:ISSN:1003-5214.0.2004-04-007
【正文快照】：
以甘油中碳酸单酯(MG)为主要成分的甘油中碳酸偏酯是一种重要的油溶性非离子表面活性剂,常作为优良的W/O型乳化剂或助乳化剂广泛应用于食品、化妆品、医药、纺织等工业[1].甘油中碳酸单酯对溶解人体胆结石有显著作用,也可用来预防和治疗腹泻,及用作亲油性营养物质、维生素K、

推荐 下载CAJ全文 下载PDF全文
CAJViewer7.0阅读器支持所有CNKI文件格式,AdobeReader仅支持PDF格式

Enzymatic Synthesis of High-purity Medium-chain Mono-glyceride
Lü Shuan-suo;FANG Yun~*;SU Ya-fen (School of Chemical & Material Engineering;Southern Yangtze University;Wuxi 214036;Jiangsu;China)
Synthesis of medium-chain partial glyceride by lipase LRI in a solvent-free system was studied.Effect of reaction conditions on conversion of medium-chain acid was investigated as well.Thus,reacting in a closed reactor for 4 h then opened for 6 h at 57 ℃,with mole ratio of acid/glycerin 1∶1.1,dosage of enzyme 100 U/g (acid) and initial dosage of water added to glycerin w(H_2O)=12%,the content of medium-chain mono-glyceride is w(MG)=42.20% in the crude product.Reducing the mole ratio of acid/ glycerin to 1∶9 and shortening the reaction time to 4 h,the content of medium-chain mono-glyceride in the purified product goes up to w(MG)=73.65% and almost free from acid and glycerin.Excess glycerin was recovered and reused,which doesn′t affect the succeeding reaction significantly,and the decrease of equilibrium conversion is less than 2%.
【Keyword】：lipase;medium-chain mono-glyceride;enzymatic synthesis